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How Sleep Helps To Repair Damaged DNA in Neurons

  • Writer: Nandita Ramesh
    Nandita Ramesh
  • May 10, 2023
  • 1 min read

During sleep, the body undergoes a variety of restorative processes that help repair and maintain healthy cellular function. One of these processes involves the repair of damaged DNA in neurons.


Neurons are highly specialized cells that are responsible for transmitting information throughout the nervous system. They are particularly vulnerable to DNA damage, which can be caused by a variety of factors, including environmental toxins, oxidative stress, and normal metabolic processes.


When DNA damage occurs in neurons, it can lead to a variety of negative consequences, including impaired cellular function and increased risk of disease. However, during sleep, the brain is able to activate certain DNA repair mechanisms that help restore damaged DNA.


One of these mechanisms is known as base excision repair, which involves the removal of damaged DNA bases and their replacement with new ones. During sleep, the brain is able to upregulate this repair mechanism, allowing for more efficient repair of damaged DNA in neurons.


In addition to base excision repair, sleep is also thought to help regulate other cellular processes that contribute to DNA repair and maintenance, including DNA replication and transcription.


Overall, sleep plays an important role in maintaining healthy cellular function, including the repair of damaged DNA in neurons. By ensuring that we get enough restful sleep each night, we can help support our body's natural repair processes and maintain optimal brain health.


See you next time,

Nandita and Sri


 
 
 

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